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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1658197Generated: November 1, 2026

Trifluoroacetic acid → HCID 178477398, compound

https://huagongshe.com/reaction/1658197

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantDicyclohexylcarbodiimideHCID 10868—
ReactantCyanomethylsulfonylacetic acidHCID 23470093—
ReactantHCID 178477375HCID 178477375—
ProductHCID 178477398HCID 178477398—

Reaction Steps

t-Butyl 7-amino-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylate (5.75 g, 15 mmol), cyanomethylsulfonylacetic acid (2.45 g, 15 mmol), and dicyclohexylcarbodiimide (3.1 g, 15 mmol) were reacted as in Example 6. The t-butyl ester was treated with trifluoroacetic acid for 20 minutes as in Example 6, to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03963711
Source datasetuspto-grants-1976_06
ORD IDord-f8e74e11928b41b5b3afab8070176eb7
Source noteuspto-grants-1976_06