HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178477398, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | Cyanomethylsulfonylacetic acid | HCID 23470093 | — |
| Reactant | HCID 178477375 | HCID 178477375 | — |
| Product | HCID 178477398 | HCID 178477398 | — |
Reaction Steps
t-Butyl 7-amino-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylate (5.75 g, 15 mmol), cyanomethylsulfonylacetic acid (2.45 g, 15 mmol), and dicyclohexylcarbodiimide (3.1 g, 15 mmol) were reacted as in Example 6. The t-butyl ester was treated with trifluoroacetic acid for 20 minutes as in Example 6, to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03963711 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-f8e74e11928b41b5b3afab8070176eb7 |
| Source note | uspto-grants-1976_06 |