Chloroacetyl chloride → HCID 21528855, compound

HRID 1658203Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1[S:9](=[O:12])(=[O:11])[NH2:10])[NH2:5].[Cl:13][CH2:14][C:15](Cl)=[O:16]>>[Cl:13][CH2:14][C:15]([NH:5][C:4]1[CH:6]=[CH:7][C:8]([S:9](=[O:12])(=[O:11])[NH2:10])=[C:2]([Cl:1])[CH:3]=1)=[O:16]

Participants

Reactant 2

HCID 6577Chloroacetyl chloride

HCID 125335224-Amino-2-chlorobenzene-1-sulfonamide

Product 1

HCID 21528855HCID 21528855, compound

Procedure

3-Chloro-4-sulphamoylaniline (20.6 g) and chloroacetyl chloride (20 ml) were refluxed 45 min and the mixture worked up as in Example 2(a) to yield 23.5 g m.p.: 214°-216°.

Workup

customto yield 23.5 g m.p.: 214°-216°

Sources & evidence

ORD record: ord-cd39048217234060bd71dbcfebab1e0f
Source dataset: uspto-grants-1976_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03963706

Reaction notes

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