HCID 21528841, compound → Benzenesulfonamide, 3-chloro-4-(2,5-dioxo-3-phenyl-1-imidazolidinyl)-

HRID 1658213Notes

Reaction equation

HRID 1658213 reaction equation
[C:1]([N:4]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH2:5][C:6]([NH:8][C:9]1[CH:14]=[CH:13][C:12]([S:15](=[O:18])(=[O:17])[NH2:16])=[CH:11][C:10]=1[Cl:19])=[O:7])(O)=[O:2]>C(OC(=O)C)(=O)C>[C:20]1([N:4]2[CH2:5][C:6](=[O:7])[N:8]([C:9]3[CH:14]=[CH:13][C:12]([S:15](=[O:18])(=[O:17])[NH2:16])=[CH:11][C:10]=3[Cl:19])[C:1]2=[O:2])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 1

HCID 21528841HCID 21528841, compound

Product 1

HCID 3041008Benzenesulfonamide, 3-chloro-4-(2,5-dioxo-3-phenyl-1-imidazolidinyl)-

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

2-(N-carboxy-phenylamino)-N-(2-chloro-4-sulphamoylphenyl)-acetamide (5.0 g) was heated in acetic anhydride (20 ml) 2 hr at 80°. The anhydride was then distilled off and the residue digested with water, filtered off and further washed with water to yield 3.5 g, m.p. 241°-243° on recrystallisation from ethyl acetate.

Workup

  1. distillationThe anhydride was then distilled off
  2. filtrationthe residue digested with water, filtered off
  3. washfurther washed with water
  4. customto yield 3.5 g, m.p. 241°-243°
  5. customon recrystallisation from ethyl acetate

Sources & evidence

ORD record
ord-1d95f692833d4a96b7f1449fc2d253fc
Source dataset
uspto-grants-1976_06
Patent number
US03963706

Reaction notes

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