Ethanol → Benzenesulfonamide, 3-chloro-4-(3-(3-methylphenyl)-5-oxo-1-imidazolidinyl)-

HRID 1658225Notes

Reaction equation

HRID 1658225 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:21]=[CH:22][CH:23]=1)[NH:5][CH2:6][C:7]([NH:9][C:10]1[CH:15]=[CH:14][C:13]([S:16](=[O:19])(=[O:18])[NH2:17])=[CH:12][C:11]=1[Cl:20])=[O:8].[CH2:24](O)C>O>[CH3:1][C:2]1[CH:3]=[C:4]([N:5]2[CH2:6][C:7](=[O:8])[N:9]([C:10]3[CH:15]=[CH:14][C:13]([S:16](=[O:19])(=[O:18])[NH2:17])=[CH:12][C:11]=3[Cl:20])[CH2:24]2)[CH:21]=[CH:22][CH:23]=1

Participants

4

Reactant 2

HCID 702EthanolHCID 21528850HCID 21528850, compound

Product 1

HCID 3041015Benzenesulfonamide, 3-chloro-4-(3-(3-methylphenyl)-5-oxo-1-imidazolidinyl)-

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2-(3-Methylanilino)-N-(2-chloro-4-sulphamoylphenyl)-acetamide 3.5 g dissolved in ethanol (100 ml) was reacted with p-formaldehyde (0.6 g) in water (200 ml) as in Example 15 (b) to yield 2.8 g product, m.p. 198°-202°C

Sources & evidence

ORD record
ord-9d792bef665d4ad5a3927f184c3e2e83
Source dataset
uspto-grants-1976_06
Patent number
US03963706

Reaction notes

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