Formaldehyde → 3-Chloro-4-(4-methyl-5-oxo-3-phenylimidazolidin-1-yl)benzene-1-sulfonamide

HRID 1658227Notes

Reaction equation

HRID 1658227 reaction equation
[NH:1]([CH:8]([CH3:23])[C:9]([NH:11][C:12]1[CH:17]=[CH:16][C:15]([S:18](=[O:21])(=[O:20])[NH2:19])=[CH:14][C:13]=1[Cl:22])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:24]=O>C(O)C>[CH3:23][CH:8]1[N:1]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:24][N:11]([C:12]2[CH:17]=[CH:16][C:15]([S:18](=[O:21])(=[O:20])[NH2:19])=[CH:14][C:13]=2[Cl:22])[C:9]1=[O:10]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 21528865HCID 21528865, compound

Product 1

HCID 30410173-Chloro-4-(4-methyl-5-oxo-3-phenylimidazolidin-1-yl)benzene-1-sulfonamide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Anilino-N-(2-chloro-4-sulfamoylphenyl)-propionamide (3.5 g) was dissolved in ethanol (100 ml) and reacted with paraformaldehyde (0,7 g) as before to yield 1.8 g, m.p. 202°C

Workup

  1. customto yield 1.8 g, m.p. 202°C

Sources & evidence

ORD record
ord-266aa75440ee404d818de7c8e425f46e
Source dataset
uspto-grants-1976_06
Patent number
US03963706

Reaction notes

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