HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Xylene → alpha-(2-Imidazolin-2-ylaminomethyl)-p-methylbenzyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Xylene | HCID 7237 | — |
| Reactant | 2-Nitroamino-2-imidazoline | HCID 410042 | — |
| Reactant | 2-Amino-1-(4-methylphenyl)ethan-1-ol | HCID 3519929 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | alpha-(2-Imidazolin-2-ylaminomethyl)-p-methylbenzyl alcohol | HCID 53928717 | — |
Reaction Conditions
| Temperature | 160 °C |
|---|
Reaction Steps
A mixture of 9.06 parts of α-(aminomethyl)-p-methylbenzyl alcohol, 7.8 parts of 2-(nitramino)-2-imidazoline and 8 parts of xylene is stirred for 30 minutes at 160°C (oil-bath). The reaction mixture is cooled and acetone is added. The precipitated product is filered off, washed with acetone and dried, yielding α-(2-imidazolin-2-ylaminomethyl)-p-methylbenzyl alcohol; 163.7°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03963718 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-4a3df0ece58b4090bbea5a90636fa23a |
| Source note | uspto-grants-1976_06 |