反应详情

To a stirred solution of 3.2 g. of 1-isopropyl-3,4,6,7-tetrahydro-4-phenyl-furo[3,2-g]quinazolin-2(1H)-one in 150 ml. of dioxane cooled to 8°±5°C. is added dropwise a solution of 2.0 g. of potassium permanganate in 130 ml. of water. After the addition is completed 1.5 ml. of formalin solution is added. The resulting precipitated solids are removed by filtration and the filtrate concentrated in vacuo to give an oil of 1-isopropyl-6,7-dihydro-4-phenyl-furo[3,2-g]quinazolin-2(1H)-one.

1. additionis added dropwise a solution of 2.0 g
2. additionAfter the addition
3. customThe resulting precipitated solids
4. customare removed by filtration
5. concentrationthe filtrate concentrated in vacuo