Acetone → 2,2,6,6-Tetramethyl-4-piperidone

Participants

Reaction Steps

A solution of 6.3 g. of acetonine in a mixed solvent comprising 30 g. of acetone and 30 g. of methanol was added with 1.6 g. of methanesulfonic acid. The mixture was maintained at room temperature for 24 hours in a sealed equipment to effect the reaction. After completion of the reaction, the reaction mixture was purified in the same manner as in Example 1 to obtain triacetonamine in a yield of 95.3%.

Provenance & Evidence