Methanethiol → HCID 20355446, compound

HRID 1658362Notes

Reaction equation

HRID 1658362 reaction equation
Cl[C:2]1[N:7]=[C:6]2[N:8]=[C:9]([C:12]([F:18])([F:17])[C:13]([F:16])([F:15])[F:14])[N:10]([OH:11])[C:5]2=[CH:4][CH:3]=1.[CH3:19][SH:20]>>[CH3:19][S:20][C:2]1[N:7]=[C:6]2[N:8]=[C:9]([C:12]([F:18])([F:17])[C:13]([F:16])([F:15])[F:14])[N:10]([OH:11])[C:5]2=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 878MethanethiolHCID 20355451HCID 20355451, compound

Product 1

HCID 20355446HCID 20355446, compound

Procedure

5-Chloro-1-hydroxy-2-(pentafluoroethyl)-1H-imidazo(4,5-b)-pyridine is reacted with methanethiol to obtain 5-(methylthio)-1-hydroxy-2-(pentafluoroethyl)-1H-imidazo(4,5-b)pyridine which is subsequently oxidized to obtain the corresponding 5-(methylsulfonyl)-1-hydroxy-2-(pentafluoroethyl)-1H-imidazo(4,5-b)-pyridine.

Sources & evidence

ORD record
ord-e95e7cccb607496299d40d843ef2910c
Source dataset
uspto-grants-1976_06
Patent number
US03963734

Reaction notes

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