Sulfuric Acid → HCID 6430998, compound

HRID 1658427Notes

Reaction equation

HRID 1658427 reaction equation
S(=O)(=O)(O)[OH:2].[CH3:6][C:7]([CH3:16])=[CH:8][CH2:9][C@@H:10]1O[C@@:11]1([CH:14]=[CH2:15])[CH3:13]>>[CH3:6][C:7]([CH3:16])=[CH:8][CH:9]([OH:2])/[CH:10]=[C:11](/[CH:14]=[CH2:15])\[CH3:13]

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 6429141HCID 6429141, compound

Product 1

HCID 6430998HCID 6430998, compoundYield 70%

Procedure

To 500 ml. of 50% aqueous sulphuric acid acid cooled between -5° and 0° were added dropwise 75 g. of transepoxyocimene prepared according to the description of paragraph a) above. The mixture was vigorously stirred for one hour while the temperature was allowed to slowly rise to 20°-25°. It was extracted with methylene chloride, the extract was washed several times with water, with a saturated aqueous solution of sodium carbonate and finally with water. The extract was dried, concentrated and distilled. Thus secondary trans-ocimenol was obtained with a yield of 70-80%.

Workup

  1. additionwere added dropwise 75 g
  2. customto slowly rise to 20°-25°
  3. extractionIt was extracted with methylene chloride
  4. washthe extract was washed several times with water
  5. customThe extract was dried
  6. concentrationconcentrated
  7. distillationdistilled

Sources & evidence

ORD record
ord-4450100e665f43268520257753319659
Source dataset
uspto-grants-1976_06
Patent number
US03963783

Reaction notes

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