反应详情

A mixture of 50 g. of N-(3-isopropoxypropyl)-p-phenylenediamine, 50 g. of 2-octyl bromide, 200 ml. of 2N sodium carbonate and 1 liter of ethanol is stirred for 18 hours at 60°C. The reaction mixture is treated with 1 liter of water and extracted with 1 liter of ether. The ether layer is separated, washed with 1200 ml. of water, dried over sodium sulfate and evaporated in vacuo. A mixture of the residue in ether is treated with hydrogen chloride gas to yield the title product in dihydrochloride salt form, m.p. 200°-202°C.

1. additionA mixture of 50 g
2. extractionextracted with 1 liter of ether
3. customThe ether layer is separated
4. washwashed with 1200 ml
5. dry with materialof water, dried over sodium sulfate
6. customevaporated in vacuo
7. additionA mixture of the residue in ether
8. additionis treated with hydrogen chloride gas