2-[5-(Pyridin-3-yl)-1,3,4-oxadiazol-2-yl]benzoic acid → 3-[5-(2-Methylphenyl)-1,3,4-oxadiazol-2-yl]pyridine

HRID 1658462Notes

Reaction equation

HRID 1658462 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[O:11][C:10]([C:12]3[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=3[C:14](O)=O)=[N:9][N:8]=2)[CH:2]=1>C(O)C>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[O:11][C:10]([C:12]3[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=3[CH3:14])=[N:9][N:8]=2)[CH:2]=1

Participants

3

Reactant 1

HCID 227649412-[5-(Pyridin-3-yl)-1,3,4-oxadiazol-2-yl]benzoic acid

Product 1

HCID 215274293-[5-(2-Methylphenyl)-1,3,4-oxadiazol-2-yl]pyridine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-[5-(3-Pyridyl)-1,3,4-oxadiazole-2-yl] benzoic acid, M.P. 213°-5° (ethanol) wt., 5g (36%). (Found: C, 62.83, 62.71; H, 3.64, 3.47; N, 16.17, 16.05. C14H9N3O3 requires, C, 62.92; H, 3.39; N, 15.73.)

Sources & evidence

ORD record
ord-6b67aaa1f57540019e05d55467ae1f2a
Source dataset
uspto-grants-1976_06
Patent number
US03964896

Reaction notes

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