反应详情

In a 500 ml flask protected with a soda lime tube is placed 10 g (0.058 mole) 1,10-diamino decane and 150 ml ether. A solution of 2.5 g (0.025 mole)n-butyl isocyanate in 25 ml ether is added and the reaction mixture stirred 1 hour. The precipitate is filtered, washed with ether, and dried to 15 g weight. Recrystallization from a mixture of 200 ml alcohol and 100 ml water gives 5.6 g white solids. An analytical sample recrystallized from acetonitrile melts at 83°-84.5°C.

1. customIn a 500 ml flask protected with a soda lime tube
2. filtrationThe precipitate is filtered
3. washwashed with ether
4. customdried to 15 g weight
5. customRecrystallization
6. additionfrom a mixture of 200 ml alcohol and 100 ml water