Dicyclohexylcarbodiimide → HCID 178477367, compound

Participants

Reaction Steps

To a solution of 7-trifluoromethylmercaptoacetamido-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid (4.70 g, 0.01 mol) and 5-indanol (1.34 g, 0.01 mol) in tetrahydrofuran is added dicyclohexylcarbodiimide (2.06 g, 0.01 mol) and the reaction is stirred for 4 hours at room temperature. The solid urea is collected and washed with tetrahydrofuran and the filtrate is evaporated to give 5-indanyl 7-trifluoromethylmercaptoacetamido-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylate.

Provenance & Evidence