HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazinecarboxylic acid, ethyl ester → HCID 68138515, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazinecarboxylic acid, ethyl ester | HCID 20064 | — |
| Reactant | 5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepine-2-thione | HCID 135667575 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68138515 | HCID 68138515 | 73% |
Reaction Steps
A solution of 1.3 g of 5-o-chlorophenyl-7-ethyl-1,2-dihydro-3H-thieno[2,3-e] [1,4]diazepine-2-thione and 0.5 g of ethoxycarbonylhydrazine in 30 ml of ethanol is refluxed for 5 hours. Then the ethanol is removed under reduced pressure, and the residue is crystallized from ligroin to give 2-ethoxycarbonylhydrazino-5-o-chlorophenyl-7-ethyl-3H-thieno[ 2,3-e] [1,4]diazepine appearing as orange crystals. The product is recrystallized from ethanol to give the pure substance melting at 207° C, in 73% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03965111 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-89237e335d594358ada691a9a2d9ed04 |
| Source note | uspto-grants-1976_06 |