化工社化工社 化学情報印刷レポート · 研究参考用
6-Chlorotryptophan → 6-Chloro-N-formyl-L-tryptophan
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6-Chlorotryptophan | HCID 65259 | — |
| 反応物 | Acetic-formic anhydride | HCID 75269 | — |
| 生成物 | 6-Chloro-N-formyl-L-tryptophan | HCID 22791070 | — |
反応手順
15 g(628 mM) of dl-6-chlorotryptophan was treated with 15 ml of acetic-formic anhydride. An exothermic reaction ensued, accompanied by solidification of the reaction slurry. Excess solvents were distilled off under vacuum and the resultant solids, after first leaching with dilute acid, were recrystallized from ethyl acetate to yield 12.45 g, 74%, of product, m.p, 181°-3° dec.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03965121 |
| 出典データセット | uspto-grants-1976_06 |
| ORD ID | ord-3b911ac8906347b0b5e4aab831a6226e |
| 出典メモ | uspto-grants-1976_06 |