HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 4-[(4-Methylphenyl)sulfanyl]benzene-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Bicarbonate | HCID 516893 | — |
| Reactant | 5-[(4-Methylphenyl)sulfanyl]-2-nitroaniline | HCID 20362819 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-[(4-Methylphenyl)sulfanyl]benzene-1,2-diamine | HCID 20362821 | — |
Reaction Steps
3.5 G. of 2-amino-4-(p-methylphenylthio)-1-nitrobenzene in 8 ml. concentrated hydrochloric acid is treated with a solution of 16 g. stannous chloride in 8 ml. concentrated hydrochloric acid in 20 ml. acetic acid. The mixture is heated for 1 hour on a steam bath, cooled and treated with potassium bicarbonate and chloroform. The mixture is filtered and the chloroform layer evaporated. The residue is triturated with hot cyclohexane giving 1,2-diamino-4-(p-methylphenylthio)-benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03965113 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-ea591a5f091c49868fb674b6c87f4474 |
| Source note | uspto-grants-1976_06 |