Sodium Hydroxide → 2-Nitro-4-phenoxyaniline

HRID 1658582Notes

Reaction equation

HRID 1658582 reaction equation
C([NH:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:7][C:6]=1[N+:18]([O-:20])=[O:19])(=O)C.[OH-].[Na+]>CO.O>[NH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:7][C:6]=1[N+:18]([O-:20])=[O:19]

Participants

5

Reactant 2

HCID 14798Sodium HydroxideHCID 3828525N-(2-nitro-4-phenoxy-phenyl)acetamide

Product 1

HCID 51737522-Nitro-4-phenoxyaniline

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

6.0 G. of 1-acetamido-2-nitro-4-phenoxybenzene and 20 ml. sodium hydroxide in methanol is warmed gently until homogeneous, diluted with water and ice, and the methanol evaporated to give 1-amino-2-nitro-4-phenoxybenzene.

Workup

  1. customthe methanol evaporated

Sources & evidence

ORD record
ord-b0603f9b24974ec2b7735cae1bedc802
Source dataset
uspto-grants-1976_06
Patent number
US03965113

Reaction notes

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