HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 68145278, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4-Methylbenzenethiol | HCID 7811 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | n-(5-chloro-2-nitrophenyl)acetamide | HCID 224170 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 68145278 | HCID 68145278 | — |
Reaction Steps
0.84 G. of 57% sodium hydride is added to 3.0 g. p-methylthiophenol in 20 ml. dimethylformamide, 4.3 G. 2-acetamido-4-chloro-1-nitrobenzene is added and the mixture heated at 140°-145°C for 5 hours, cooled and treated with water. The crude product is filtered off, washed with water and pentane. Recrystallization from methanol gives 2-acetamido-4-(p-methylthiophenoxy)-1-nitrobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03965113 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-bdd2278fb9d34143a360ad33e7329c78 |
| Source note | uspto-grants-1976_06 |