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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1658618Generated: October 25, 2026

Ammonium → 3-cyano-3-Hydroxy-4-Chlorobutyric Acid

https://huagongshe.com/reaction/1658618

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantHydrogen CyanideHCID 768—
ReactantButanoic acid, 4-chloro-3-oxo-HCID 119720—
Product3-cyano-3-Hydroxy-4-Chlorobutyric AcidHCID 21528067—

Reaction Steps

In an alternate procedure, the 3-oxo-4-chlorobutyric acid from 11 is reacted at 12 directly with HCN in the absence of ammonium or metal cations to produce 3-cyano-3-hydroxy-4-chlorobutyric acid for feed to hydrolysis step 15.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03965168
Source datasetuspto-grants-1976_06
ORD IDord-dfed2722185248e3ba33c17a15e2f308
Source noteuspto-grants-1976_06