反应详情

N-Acetyl-2-aminomethyl-3-methylthiophene is dissolved in carbon tetrachloride and treated with an equimolar amount of N-bromosuccinimide and a catalytic amount of dibenzoyl peroxide. The mixture is heated to reflux for 3 hours while irradiating with a 250 watt light. The mixture is cooled and the precipitated succinimide removed by filtration. The filtrate is washed with saturated sodium bisulphite solution, dried over magnesium sulfate and evaporated to yield the title compound.

1. temperatureThe mixture is heated
2. temperatureto reflux for 3 hours
3. customwhile irradiating with a 250 watt light
4. temperatureThe mixture is cooled
5. customthe precipitated succinimide removed by filtration
6. washThe filtrate is washed with saturated sodium bisulphite solution
7. dry with materialdried over magnesium sulfate
8. customevaporated