Acetic Anhydride → HCID 21525466, compound

HRID 1658729Notes

Reaction equation

HRID 1658729 reaction equation
Cl.[OH:2][CH2:3][CH2:4][O:5][C:6]1[CH:7]=[N:8][C:9]([C:12]2[N:13]([CH3:20])[C:14]([N+:17]([O-:19])=[O:18])=[CH:15][N:16]=2)=[N:10][CH:11]=1.[C:21](OC(=O)C)(=[O:23])[CH3:22]>O>[C:21]([O:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[N:10][C:9]([C:12]2[N:13]([CH3:20])[C:14]([N+:17]([O-:19])=[O:18])=[CH:15][N:16]=2)=[N:8][CH:7]=1)(=[O:23])[CH3:22]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 21525460HCID 21525460, compound

Product 1

HCID 21525466HCID 21525466, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.29 g. (1 millimole) of 5-(2-hydroxyethoxy)-2-(5-nitro-1-methyl-2-imidazolyl)-pyrimidine hydrochloride is heated in 3 ml. of acetic anhydride to 100° C. for 1 hour. After cooling, the reaction mixture is introduced into water and the product is filtered off; m.p. 148°-150° C.

Workup

  1. temperatureAfter cooling
  2. filtrationthe product is filtered off

Sources & evidence

ORD record
ord-30a1efdba5cd438c95ca451064ea8308
Source dataset
uspto-grants-1976_06
Patent number
US03966732

Reaction notes

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