HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminopyrimidine → 2-Amino-1-[[(o-bromophenyl)thio]methyl]pyrimidinium chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminopyrimidine | HCID 7978 | — |
| Reactant | 1-Bromo-2-[(chloromethyl)sulfanyl]benzene | HCID 21828494 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 2-Amino-1-[[(o-bromophenyl)thio]methyl]pyrimidinium chloride | HCID 21393395 | 81.2% |
Reaction Steps
To a solution of 14.1 g of 2-aminopyrimidine in 180 ml of xylene is added a solution of 24.0 g of o-bromophenyl chloromethyl sulfide in 40 ml of xylene. The mixture is heated at 90°-95° for about 15 hours to give about 27.3 g of the named compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966733 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-4f68d423a7c64730a0db311b0ca38096 |
| Source note | uspto-grants-1976_06 |