HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminopyrimidine → 2-Amino-1-[[(2-bromo-5-chlorophenyl)thio]methyl]pyrimidinium chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminopyrimidine | HCID 7978 | — |
| Reactant | 2-Bromo-5-chlorophenyl chloromethyl sulfide | HCID 21393391 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 2-Amino-1-[[(2-bromo-5-chlorophenyl)thio]methyl]pyrimidinium chloride | HCID 21393389 | 86.5% |
Reaction Steps
To a solution of 18.8 g of 2-aminopyrimidine in 180 ml of benzene is added 54.6 g of the product from example 25, and the mixture stirred and heated under reflux for about 12 hours. The cooled mixture is filtered to give about 62.8 g of the named compound, mp about 240°-242°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966733 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-c1a9d78b7ae94a9880ebf713eb0a7b46 |
| Source note | uspto-grants-1976_06 |