HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl (ethoxymethylene)malonate → HCID 68131296, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | 1-[(Pyridin-4-yl)methyl]-1H-pyrazol-5-amine | HCID 1096898 | — |
| Product | HCID 68131296 | HCID 68131296 | 65% |
Reaction Steps
174 g of 1-(4-picolyl)-5-aminopyrazole and 216 g of ethoxymethylene malonic acid diethyl ester are heated with stirring at 140°, until the theoretical amount of alcohol has distilled off. The reaction mixture crystallizes on cooling. Recrystallization from ethyl acetate yields 220 g of [[[1-(4-picolyl)-5-pyrazolyl]amino]methylene]malonic acid diethyl ester (65%), m.p. 95°-97°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966746 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-61230c65213f423894c3276f5fcf490a |
| Source note | uspto-grants-1976_06 |