HuagongsheHuagongshe Chemistry Print Report · For research reference only
Selenium Dioxide → HCID 178469709, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Selenium Dioxide | HCID 24007 | — |
| Reactant | 4-picolyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester | HCID 86733605 | — |
| Catalyst | Water | HCID 962 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178469709 | HCID 178469709 | — |
Reaction Steps
3 g of 4-hydroxy-1-(4-picolyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester (0.01 mol) is dissolved in 20 ml of acetic acid. 2.2 g of selenium dioxide (0.02 mol) and 2-3 drops of water are added. The mixture is refluxed for 30 minutes and then filtered off. 4-Hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester precipitates on cooling. Recrystallization from acetic acid yields 1.8 g (87%), m.p. 275°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966746 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-1be135eccc06414f836f90eccde4a3ec |
| Source note | uspto-grants-1976_06 |