Phosphorus sulfide (P2S5) → HCID 21525519, compound

HRID 1658769Notes

Reaction equation

HRID 1658769 reaction equation
[CH2:1]([N:4]([CH2:8][C:9]([N:11]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[NH:15][C:14](=O)[C:13]2[CH:23]=[CH:24][CH:25]=[N:26][C:12]1=2)=[O:10])[CH2:5][CH2:6][CH3:7])[CH2:2][CH3:3].P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:28]>N1C=CC=CC=1>[CH2:1]([N:4]([CH2:8][C:9]([N:11]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[NH:15][C:14](=[S:28])[C:13]2[CH:23]=[CH:24][CH:25]=[N:26][C:12]1=2)=[O:10])[CH2:5][CH2:6][CH3:7])[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 14817Phosphorus sulfide (P2S5)HCID 21525507HCID 21525507, compound

Product 1

HCID 21525519HCID 21525519, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

In the manner given in Example 1, 6,11-dihydro-11-[(dipropylamino)acetyl]-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one is reacted with phosphorus pentasulfide in pyridine to give 6,11-dihydro-11-[(dipropylamino)acetyl]-5H-pyrido[2,3-b][1,5]benzodiazepin-5-thione.

Sources & evidence

ORD record
ord-146c7faee7104d6d9c5716a044569abf
Source dataset
uspto-grants-1976_06
Patent number
US03966736

Reaction notes

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