Phosphorus sulfide (P2S5) → HCID 21525542, compound

HRID 1658772Notes

Reaction equation

HRID 1658772 reaction equation
[Br:1][C:2]1[C:3]([Br:26])=[CH:4][C:5]2[N:11]([C:12](=[O:19])[CH2:13][N:14]([CH2:17][CH3:18])[CH2:15][CH3:16])[C:10]3[N:20]=[CH:21][CH:22]=[CH:23][C:9]=3[C:8](=O)[NH:7][C:6]=2[CH:25]=1.P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:28]>N1C=CC=CC=1>[Br:1][C:2]1[C:3]([Br:26])=[CH:4][C:5]2[N:11]([C:12](=[O:19])[CH2:13][N:14]([CH2:17][CH3:18])[CH2:15][CH3:16])[C:10]3[N:20]=[CH:21][CH:22]=[CH:23][C:9]=3[C:8](=[S:28])[NH:7][C:6]=2[CH:25]=1

Participants

4

Reactant 2

HCID 14817Phosphorus sulfide (P2S5)HCID 21525522HCID 21525522, compound

Product 1

HCID 21525542HCID 21525542, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

In the manner given in Example 1, 8,9-dibromo-6,11-dihydro-11-[(diethylamino)acetyl]-5H-pyrido[2,3-b][1,5]-benzodiazepin-5-one is reacted with phosphorus pentasulfide in pyridine to give 8,9-dibromo-6,11-dihydro-11-[(diethylamino)acetyl]-5H-pyrido[2,3-b][1,5]benzodiazepin-5-thione.

Sources & evidence

ORD record
ord-762e10ef5755444395c18dc7e1a9f576
Source dataset
uspto-grants-1976_06
Patent number
US03966736

Reaction notes

Loading…