Phosphorus sulfide (P2S5) → HCID 21525509, compound

HRID 1658774Notes

Reaction equation

HRID 1658774 reaction equation
[N:1]1([CH2:6][C:7]([N:9]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[NH:13][C:12](=O)[C:11]3[CH:21]=[CH:22][CH:23]=[N:24][C:10]2=3)=[O:8])[CH2:5][CH2:4][CH2:3][CH2:2]1.P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:26]>N1C=CC=CC=1>[N:1]1([CH2:6][C:7]([N:9]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[NH:13][C:12](=[S:26])[C:11]3[CH:21]=[CH:22][CH:23]=[N:24][C:10]2=3)=[O:8])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 14817Phosphorus sulfide (P2S5)HCID 21525514HCID 21525514, compound

Product 1

HCID 21525509HCID 21525509, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

In the manner given in Example 1, 6,11-dihydro-11-(pyrrolidinoacetyl)-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one is reacted with phosphorus pentasulfide in pyridine to give 6,11-dihydro-11-(pyrrolidinoacetyl)-5H-pyrido-[2,3-b][1,5]benzodiazepin-5-thione.

Sources & evidence

ORD record
ord-0c5edeca0b0b43309708614e1b11ad92
Source dataset
uspto-grants-1976_06
Patent number
US03966736

Reaction notes

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