Phosphorus sulfide (P2S5) → HCID 21525538, compound

HRID 1658775Notes

Reaction equation

HRID 1658775 reaction equation
[N:1]1([CH2:7][C:8]([N:10]2[C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=3[NH:14][C:13](=O)[C:12]3[CH:22]=[CH:23][CH:24]=[N:25][C:11]2=3)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:27]>N1C=CC=CC=1>[N:1]1([CH2:7][C:8]([N:10]2[C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=3[NH:14][C:13](=[S:27])[C:12]3[CH:22]=[CH:23][CH:24]=[N:25][C:11]2=3)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 14817Phosphorus sulfide (P2S5)HCID 21525555HCID 21525555, compound

Product 1

HCID 21525538HCID 21525538, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

In the manner given in Example 1, 6,11-dihydro-11-(piperidinoacetyl)-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one is reacted with phosphorus pentasulfide in pyridine to give 6,11-dihydro-11-(piperidinoacetyl)-5H-pyrido-[2,3-b][1,5]benzodiazepin-5-thione.

Sources & evidence

ORD record
ord-af81c587cf80490f94238a9099af0ce2
Source dataset
uspto-grants-1976_06
Patent number
US03966736

Reaction notes

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