Phosphorus sulfide (P2S5) → HCID 21525516, compound

HRID 1658776Notes

Reaction equation

HRID 1658776 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([CH2:8][C:9]([N:11]2[C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=3[NH:15][C:14](=O)[C:13]3[CH:23]=[CH:24][CH:25]=[N:26][C:12]2=3)=[O:10])[CH2:4][CH2:3]1.P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:28]>N1C=CC=CC=1>[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([CH2:8][C:9]([N:11]2[C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=3[NH:15][C:14](=[S:28])[C:13]3[CH:23]=[CH:24][CH:25]=[N:26][C:12]2=3)=[O:10])[CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 14817Phosphorus sulfide (P2S5)HCID 14054145HCID 14054145, compound

Product 1

HCID 21525516HCID 21525516, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

In the manner given in Example 1, 6,11-dihydro-11-[(4-methylpiperazino)acetyl]-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one is reacted with phosphorus pentasulfide in pyridine to give 6,11-dihydro-11-[(4-methylpiperazino)-acetyl]-5H-pyrido[2,3-b][1,5]benzodiazepin-5-thione.

Sources & evidence

ORD record
ord-ca565f4fc1e147ea94c6ccf903359610
Source dataset
uspto-grants-1976_06
Patent number
US03966736

Reaction notes

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