Hydrazinecarboxylic acid, ethyl ester → HCID 21525565, compound

HRID 1658780Notes

Reaction equation

HRID 1658780 reaction equation
[CH2:1]([N:4]([CH2:8][C:9]([N:11]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[NH:15][C:14](=S)[C:13]2[CH:23]=[CH:24][CH:25]=[N:26][C:12]1=2)=[O:10])[CH2:5][CH2:6][CH3:7])[CH2:2][CH3:3].[C:27](OCC)(=[O:30])[NH:28][NH2:29]>>[CH2:1]([N:4]([CH2:8][C:9]([N:11]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[N:15]2[C:27](=[O:30])[NH:28][N:29]=[C:14]2[C:13]2[CH:23]=[CH:24][CH:25]=[N:26][C:12]1=2)=[O:10])[CH2:5][CH2:6][CH3:7])[CH2:2][CH3:3]

Participants

3

Reactant 2

HCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 21525519HCID 21525519, compound

Product 1

HCID 21525565HCID 21525565, compound

Procedure

In the manner given in Example 13, 6,11-dihydro-11-[(dipropylamino)acetyl]5H-pyrido[2,3-b][1,5]benzodiazepin-5-thione is heated to about 200° C. with ethyl carbazate to give 2,9-dihydro-9-[(dipropylamino)acetyl]-3H-pyrido-[3,2-c]-s-triazolo[4,3-a][1,5]benzodiazepin-3-one.

Sources & evidence

ORD record
ord-29f65c419b494ca2929f19a491d4550d
Source dataset
uspto-grants-1976_06
Patent number
US03966736

Reaction notes

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