Hydrazinecarboxylic acid, ethyl ester → HCID 21525518, compound

HRID 1658782Notes

Reaction equation

HRID 1658782 reaction equation
[Cl:1][C:2]1[C:3]([Cl:28])=[CH:4][C:5]2[N:11]([C:12](=[O:21])[CH2:13][N:14]([CH2:18][CH2:19][CH3:20])[CH2:15][CH2:16][CH3:17])[C:10]3[N:22]=[CH:23][CH:24]=[CH:25][C:9]=3[C:8](=S)[NH:7][C:6]=2[CH:27]=1.[C:29](OCC)(=[O:32])[NH:30][NH2:31]>>[Cl:1][C:2]1[C:3]([Cl:28])=[CH:4][C:5]2[N:11]([C:12](=[O:21])[CH2:13][N:14]([CH2:18][CH2:19][CH3:20])[CH2:15][CH2:16][CH3:17])[C:10]3[N:22]=[CH:23][CH:24]=[CH:25][C:9]=3[C:8]3[N:7]([C:29](=[O:32])[NH:30][N:31]=3)[C:6]=2[CH:27]=1

Participants

3

Reactant 2

HCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 21525556HCID 21525556, compound

Product 1

HCID 21525518HCID 21525518, compound

Procedure

In the manner given in Example 13, 8,9-dichloro-6,11-dihydro-11-[(dipropylamino)acetyl]-5H-pyrido[2,3-b][1,5]-benzodiazepin-5-thione is heated to about 200° C. with ethyl carbazate to give 6,7-dichloro-2,9-dihydro-9-[(dipropylamino)acetyl]-3H-pyrido[3,2-c]-s-triazolo-[4,3-a][1,5]benzodiazepin-3-one.

Sources & evidence

ORD record
ord-95dd1afbe1ab4b86b92eed377bcbcf7d
Source dataset
uspto-grants-1976_06
Patent number
US03966736

Reaction notes

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