Hydrazinecarboxylic acid, ethyl ester → HCID 21525562, compound

HRID 1658785Notes

Reaction equation

HRID 1658785 reaction equation
[N:1]1([CH2:6][C:7]([N:9]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[NH:13][C:12](=S)[C:11]3[CH:21]=[CH:22][CH:23]=[N:24][C:10]2=3)=[O:8])[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:25](OCC)(=[O:28])[NH:26][NH2:27]>>[N:1]1([CH2:6][C:7]([N:9]2[C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[N:13]3[C:25](=[O:28])[NH:26][N:27]=[C:12]3[C:11]3[CH:21]=[CH:22][CH:23]=[N:24][C:10]2=3)=[O:8])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 21525509HCID 21525509, compound

Product 1

HCID 21525562HCID 21525562, compound

Procedure

In the manner given in Example 13, 6,11-dihydro-11-(pyrrolidinoacetyl)-5H-pyrido[2,3-b][1,5]benzodiazepin-5-thione is heated to about 200° C. with ethyl carbazate to give 2,9-dihydro-9-(pyrrolidinoacetyl)-3H-pyrido[3,2-c]-s-triazolo[4,3-a][1,5]benzodiazepin-3-one.

Sources & evidence

ORD record
ord-6be3e73ca7fb49739d6e435ac8ff40ea
Source dataset
uspto-grants-1976_06
Patent number
US03966736

Reaction notes

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