HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylpropanolamine → Penicillamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylpropanolamine | HCID 10297 | — |
| Reactant | HCID 21512080 | HCID 21512080 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Penicillamine | HCID 5852 | — |
Reaction Steps
The procedure of Example 1 was followed, however, using 21.8 grams (0.1 mole) of N-formyl-isopropylidene-D,L-penicillamine and 15.1 grams (0.1 mole) of 1-norephedrine and using 150 ml of acetone as the solvent. There were obtained 28.5 grams (equal to 78%) of the adduct (1) having a melting point of 200°-204°C. and [α]D20 + 31°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966752 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-1459db0873314c96845b8213c4af2d16 |
| Source note | uspto-grants-1976_06 |