反应详情

Nitroethane (3g; 40 m mole) in ethanol (120 ml) was heated under reflux and under nitrogen for 10 minutes with benzyltrimethyl ammonium hydroxide (1 ml) and then cooled to room temperature. Acryloylferrocene (6.5g; 27.1 mole) was then added and the solution was stirred for 1 hour and then filtered. The filtrate was concentrated on the rotary evaporator, then poured into water and extracted with chloroform. The organic extract was washed (water) and dried (sodium sulphate) to give a brown solid which was recrystallised from cyclohexane/petroleum ether to give 4-nitropentanoyl ferrocene (1.65g; 19.2%) mp 79°-80°.

1. filtrationfiltered
2. concentrationThe filtrate was concentrated on the rotary evaporator
3. additionpoured into water
4. extractionextracted with chloroform
5. extractionThe organic extract
6. washwas washed (water)
7. dry with materialdried (sodium sulphate)
8. customto give a brown solid which
9. customwas recrystallised from cyclohexane/petroleum ether