HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pentanone → 1-Bromo-trans-1-octen-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pentanone | HCID 7895 | — |
| Reactant | Lithium Bromide | HCID 82050 | — |
| Reactant | 1-Chloro-trans-1-octen-3-one | HCID 11041003 | — |
| Product | 1-Bromo-trans-1-octen-3-one | HCID 11790338 | — |
Reaction Steps
A mixture of 68.0 g. (0.424 mole) of 1-chloro-trans-1-octen-3 one (Example 723) and 444 g. (4.24 moles) of anhydrous lithium bromide in 900 ml. of 2-pentanone is refluxed for 30 minutes, cooled, and partitioned between ice water and ether. The organic phase is washed with water and saturated brine, dried (NaSO4), and evaporated to an oil. This material is used directly without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966773 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-373c78359f3546b5a6b33be0cc51dded |
| Source note | uspto-grants-1976_06 |