HCID 21137946, compound → HCID 21525989, compound

HRID 1659084Notes

Reaction equation

HRID 1659084 reaction equation
[C:1]([S-:4])(=[S:3])[CH3:2].[Na+].Cl[CH:7]([CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[Cl:27])=[CH:17][CH:16]=1)[C:8]([O:10][CH2:11][CH3:12])=[O:9]>C(O)C>[C:1]([S:4][CH:7]([CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[Cl:27])=[CH:17][CH:16]=1)[C:8]([O:10][CH2:11][CH3:12])=[O:9])(=[S:3])[CH3:2]

Participants

4

Reactant 2

HCID 21137946HCID 21137946, compoundHCID 21526152HCID 21526152, compound

Product 1

HCID 21525989HCID 21525989, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 0.2 moles of sodium dithioacetate and 0.12 moles of ethyl α-chloro-γ-(2'-chloro-4-biphenylyl)butyrate in 300 ml. of absolute ethanol is stirred at room temperature for 15 hours. The reaction mixture is filtered, washed with absolute ethanol and evaporated to dryness in vacuo. The residue is treated with ether, filtered and evaporated to obtain ethyl α-thioacetylthio-γ-(2'-chloro-4-biphenylyl)butyrate.

Workup

  1. filtrationThe reaction mixture is filtered
  2. washwashed with absolute ethanol
  3. customevaporated to dryness in vacuo
  4. additionThe residue is treated with ether
  5. filtrationfiltered
  6. customevaporated

Sources & evidence

ORD record
ord-d33fa4d0c6ae418db0687e5f06755862
Source dataset
uspto-grants-1976_06
Patent number
US03966801

Reaction notes

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