Acetic Anhydride → HCID 86733628, compound

HRID 1659099Notes

Reaction equation

HRID 1659099 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[CH2:11][S:10][C:9]2=[S:14])=[CH:4][CH:3]=1.C(C(CC)(CC)C([O-])([O-])[O-])C.[C:26]([O:29][C:30](=O)[CH3:31])(=O)[CH3:27]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[C:12](=[O:13])[C:11](=[C:26]([O:29][CH2:30][CH3:31])[CH3:27])[S:10][C:9]2=[S:14])=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 83070Rhodanine, 3-(4-chlorophenyl)-HCID 21875354Triethylorthoaceate

Product 1

HCID 86733628HCID 86733628, compound

Procedure

A mixture of 50 g. (0.2 m.) of the above-prepared rhodanine and 140 g. (0.86 m.) of triethylorthoacetate in 350 ml. of acetic anhydride is refluxed for four hours. The cooled reaction solution is filtered and the product is washed with 100 ml. of 70% aqueous acetic acid to yield 3-(4'-chlorophenyl)-5-(1'-ethoxyethylidene)-rhodanine, m.p. 168°-171°C.

Workup

  1. additionA mixture of 50 g
  2. customThe cooled reaction solution
  3. filtrationis filtered
  4. washthe product is washed with 100 ml

Sources & evidence

ORD record
ord-d4caa5e4fd9541e895e3826e886540c3
Source dataset
uspto-grants-1976_06
Patent number
US03966942

Reaction notes

Loading…