HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thioglycolic Acid → 3-Decoxypropanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thioglycolic Acid | HCID 1133 | — |
| Reactant | 1,2-Dichloro-4-isothiocyanatobenzene | HCID 23065 | — |
| Catalyst | Triethylamine | HCID 8471 | — |
| Product | 3-Decoxypropanenitrile | HCID 99466 | — |
Reaction Steps
A mixture of 6.12 g. (0.03 m.) of 3,4-dichlorophenyl isothiocyanate, 2.8 ml. (3.68 g., 0.04 m.) of mercaptoacetic acid and a few drops of triethylamine is heated in a pressure bottle at 110°-130°C. for 2 hours. The cooled reaction mixture is filtered to give 3-(3',4'-dichlorophenyl)-rhodanine, m.p. 176°-178°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966942 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-9e441cbd89344df19947564bea600069 |
| Source note | uspto-grants-1976_06 |