Bromine → HCID 178526237, compound

HRID 1659116Notes

Reaction equation

HRID 1659116 reaction equation
[CH3:1][C:2]1[CH:11]=[N+:10]([O-:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N+:3]=1[O-:13].[Br:14]Br>CO>[Br:14][CH2:1][C:2]1[CH:11]=[N+:10]([O-:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N+:3]=1[O-:13]

Participants

4

Reactant 2

HCID 24408BromineHCID 178430958HCID 178430958, compound

Product 1

HCID 178526237HCID 178526237, compoundYield 32%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a thick slurry of 106 g. (0.6 mole) of 2-methyl quinoxaline 1,4-dioxide in 400 ml of methanol was added with stirring over a period of 1 hour, 96 g. (0.6 mole) of bromine. The reaction was then stirred for 5 days at room temperature. The reaction mixture was filtered and the collected yellow solid was washed with 200 ml. of ether. This solid was air dried to obtain 50 g. (32percent yield of the title compound, mp-158°-159°.

Workup

  1. stirringThe reaction was then stirred for 5 days at room temperature
  2. filtrationThe reaction mixture was filtered
  3. washthe collected yellow solid was washed with 200 ml
  4. customdried
  5. customto obtain 50 g

Sources & evidence

ORD record
ord-09c87078a3fa41e987476ec1597c09ca
Source dataset
uspto-grants-1976_06
Patent number
US03966951

Reaction notes

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