Bromine → HCID 178465859, compound

HRID 1659117Notes

Reaction equation

HRID 1659117 reaction equation
[C:1]([C:4]1[C:13]([CH3:14])=[N+:12]([O-:15])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]=1[O-:16])(=[O:3])[CH3:2].[Br:17]Br>CO>[C:1]([C:4]1[C:13]([CH2:14][Br:17])=[N+:12]([O-:15])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]=1[O-:16])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 24408BromineHCID 178466988HCID 178466988, compound

Product 1

HCID 178465859HCID 178465859, compoundYield 71%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a stirred suspension of 2-acetyl-3-methyl-quinoxaline-1,4-dioxide (343 g. 1.57 mole) in 3 l. of methanol was added 89 ml. (1.74 mole) of bromine over a period of two hours. The reaction mixture was then stirred for five days at room temperature. The resulting yellow solid was collected by suction filtration, washed with methanol and ether, and dried to give 331 g. (71 percent yield) of the title compound, mp -164°-166° .

Workup

  1. filtrationThe resulting yellow solid was collected by suction filtration
  2. washwashed with methanol and ether
  3. customdried
  4. customto give 331 g

Sources & evidence

ORD record
ord-fc9a1a2239f54134957d22b3d185596d
Source dataset
uspto-grants-1976_06
Patent number
US03966951

Reaction notes

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