Bromine → HCID 178526280, compound

HRID 1659118Notes

Reaction equation

HRID 1659118 reaction equation
[OH:1][CH2:2][C:3]1[C:12]([CH3:13])=[N+:11]([O-:14])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N+:4]=1[O-:15].[Br:16]Br>CO>[OH:1][CH2:2][C:3]1[C:12]([CH2:13][Br:16])=[N+:11]([O-:14])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N+:4]=1[O-:15]

Participants

4

Reactant 2

HCID 24408BromineHCID 178429581HCID 178429581, compound

Product 1

HCID 178526280HCID 178526280, compoundYield 62%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a stirred suspension of 2-hyroxymethyl-3-methylquinoxaline-1,4-dioxide (10.3 g., 0.05 mole) in 100 ml. of methanol was added 1.5 ml. (0.055 mole) of bromine over a period of ten minutes at room temperature. The reaction mixture was then stirred for two days. The resulting yellow solid was collected, washed with methanol and ether, and air dried to give 8.9 g. (62 percent yield of the title compound, mp-138°-140°.

Workup

  1. customThe resulting yellow solid was collected
  2. washwashed with methanol and ether, and air
  3. customdried
  4. customto give 8.9 g

Sources & evidence

ORD record
ord-a01ac0482cbb49048cf228dfa13c95ca
Source dataset
uspto-grants-1976_06
Patent number
US03966951

Reaction notes

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