Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrogen Sulfide | HCID 402 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 21486893 | HCID 21486893 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 54052991 | HCID 54052991 | — |
Reaction Steps
2 grams of 3-methoxy-2-(2-pyridyl)propionitrile is dissolved in 1.5 g. of triethylamine and 2 g. of dry pyridine, saturated with hydrogen sulfide. The mixture is heated at 100°C. in a sealed bomb for 15 hours. The mixture is cooled, diluted with water and extracted with ether. The organic phase is dried, the solvent is removed and the residue is recrystallized from benzene/petroleum ether to give 3-methoxy-2-(2-pyridyl)thiopropanamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03966945 |
|---|
| Source dataset | uspto-grants-1976_06 |
|---|
| ORD ID | ord-c333b347319c4433b90720ef8a57ad70 |
|---|
| Source note | uspto-grants-1976_06 |
|---|
