HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 2-methoxy-N,N-dimethyl-2-(2-pyridyl)thioacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Phosphorus sulfide (P2S5) | HCID 14817 | — |
| Reactant | HCID 21486904 | HCID 21486904 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-methoxy-N,N-dimethyl-2-(2-pyridyl)thioacetamide | HCID 15581959 | — |
Reaction Steps
Phosphorus pentasulfide (4 g.) is added to 9.7 g. of 2-methoxy-N,N-dimethyl-2-(2-pyridyl)acetamide in 25 ml. of pyridine. The mixture is heated on a steam bath for 2 hours, then 250 ml. of water and 10 ml. of 5% aqueous sodium hydroxide solution are added. The mixture is extracted with chloroform and the extracts are dried and concentrated and the residue is recrystallized to give 2-methoxy-N,N-dimethyl-2-(2-pyridyl)thioacetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966945 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-f5df8a436e44409cb6525f0d39749bc1 |
| Source note | uspto-grants-1976_06 |