HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroethyl isocyanate → 3-Ethyl-2-[O-(2-chloroethylcarbamoyl)-oximino]-4-thiazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroethyl isocyanate | HCID 16035 | — |
| Reactant | 3-Ethyl-2-oximino-4-thiazolidinone | HCID 73795300 | — |
| Catalyst | Triethylamine | HCID 8471 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-Ethyl-2-[O-(2-chloroethylcarbamoyl)-oximino]-4-thiazolidinone | HCID 54479184 | — |
Reaction Steps
A solution of 2.0 g, 3-ethyl-2-oximino-4-thiazolidinone in 100 ml chloroform, 50 ml acetonitrile, 1.32 g., 2-chloroethylisocyanate and 2 drops of triethyl amine was placed in a pressure bottle and left standing overnight at ambient temperature. Concentration yielded 3.0 g of product. Recrystallized from isopropylether - ethyl acetate, m.p. 99°-102°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966953 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-1600141bb9f34af684982901b647bc70 |
| Source note | uspto-grants-1976_06 |