HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Isocyanate → HCID 53921615, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 3-(Dimethylamino)-2-(hydroxyimino)-5-methyl-1,3-thiazolidin-4-one | HCID 71396852 | — |
| Catalyst | Triethylamine | HCID 8471 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 53921615 | HCID 53921615 | 325.6% |
Reaction Steps
A solution of 1.18 g of 3-dimethylamino-5-methyl-2-oximino-4-thiazolidinone in 50 ml acetone, 1.0 g methylisocyanate and 2 drops of triethylamine was placed in a pressure bottle and left standing at room temperature. After 20 hours additional 0.75 ml of methylisocyanate and 2 drops of triethylamine were added and left standing for 24 hours. Concentration yielded 5.0 g of crude product. Crystallized from methylene chloride and isopropyl ether, m.p. 110°-113°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03966953 |
| Source dataset | uspto-grants-1976_06 |
| ORD ID | ord-0b5341acea2441dd8c3c57e6ff87a41d |
| Source note | uspto-grants-1976_06 |