Sodium Hydroxide → HCID 12264816, compound

HRID 1659189Notes

Reaction equation

HRID 1659189 reaction equation
CC[O:3][C:4]([C:6]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH3:16])[C:10]=1[C:17]([NH2:19])=[O:18])=[O:7])=[O:5].[OH-].[Na+]>O>[CH3:16][O:15][C:11]1[C:10]([C:17]([NH2:19])=[O:18])=[C:9]([NH:8][C:6]([C:4]([OH:5])=[O:3])=[O:7])[CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 198325Wy 16,922

Product 1

HCID 12264816HCID 12264816, compoundYield 59.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2'-Carbamoyl-3'-methoxyoxanilic acid ethyl ester (1.33 g, 0.005 mole) is stirred in 50 ml water, and 5.0 ml of N NaOH is slowly added, giving a solution. After 1/2 hour the solution is filtered, and the filtrate is acidified to pH 2 with N HCl, giving 0.71 g of the title compound, m.p. 214°-215°C., after crystallization from ethanol.

Workup

  1. customgiving a solution
  2. filtrationAfter 1/2 hour the solution is filtered

Sources & evidence

ORD record
ord-ac874f25b8434da2bea12a7c00697cda
Source dataset
uspto-grants-1976_06
Patent number
US03966965

Reaction notes

Loading…