Ammonia → HCID 12264817, compound

HRID 1659190Notes

Reaction equation

HRID 1659190 reaction equation
CC[O:3][C:4]([C:6]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH3:16])[C:10]=1[C:17]([NH2:19])=[O:18])=[O:7])=O.[NH3:20]>C(O)C>[C:17]([C:10]1[C:11]([O:15][CH3:16])=[CH:12][CH:13]=[CH:14][C:9]=1[NH:8][C:6]([C:4]([NH2:20])=[O:3])=[O:7])(=[O:18])[NH2:19]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 198325Wy 16,922

Product 1

HCID 12264817HCID 12264817, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2'-Carbamoyl-3'-methoxyoxanilic acid ethyl ester (5.0 g, 0.0188 mole) is added to 50 ml of ethanol saturated with ammonia at 0°-5°C., and the mixture is stirred in an ice-bath for 2 hours, then filtered. The cake is washed with ethanol, giving 1.41 g of the title compound, m.p. 252°-255°C., after crystallization from water.

Workup

  1. filtrationfiltered
  2. washThe cake is washed with ethanol

Sources & evidence

ORD record
ord-f9249edca1a84ca4a86dd0317a6d8d8b
Source dataset
uspto-grants-1976_06
Patent number
US03966965

Reaction notes

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