Ethyl 3-furoate → N-{2-[2-(1-Methylpiperidin-2-yl)ethyl]phenyl}furan-3-carboxamide

Participants

Reaction Steps

Reaction of ethyl furan-3-carboxylate prepared by the method of Boyd et al, Synthesis, 545, (Oct. 1971) with 2-(2-aminophenethyl)-1-methylpiperidine according to the procedure of Example 115 provides 2'-[2-(1-methyl-2-piperidyl)ethyl]-3-furancarboxanilide, m.p. 114.5°-115.5° C. (corr.), from isopropyl ether and then ethyl acetate.

Provenance & Evidence